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Interpreting CT perfusion in stroke
  1. Stevan Christopher Wing1,
  2. Hugh S Markus2
  1. 1 Department of Neurology, Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK
  2. 2 Department of Clinical Neurosciences, University of Cambridge, Cambridge, UK
  1. Correspondence to Dr Stevan Christopher Wing, Department of Neurology, Cambridge University Hospitals, NHS Foundation Trust, Cambridge CB2 0QQ, UK; stevan.wing{at}


CT perfusion images can be rapidly obtained on all modern CT scanners and easily incorporated into an acute stroke imaging protocol. Here we discuss the technique of CT perfusion imaging, how to interpret the data and how it can contribute to the diagnosis of acute stroke and selection of patients for treatment. Many patients with acute stroke are excluded from reperfusion therapy if the onset time is not known or if they present outside of traditional treatment time windows. There is a growing body of evidence supporting the use of perfusion imaging in these patients to identify patterns of brain perfusion that are favourable for recanalisation therapy.

  • stroke
  • cerebral blood flow
  • cerebrovascular disease
  • fibrinolysis
  • neuroradiology

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  • Contributors SCW wrote the manuscript. SCW and HSM revised the manuscript.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Competing interests None declared.

  • Patient consent Not required.

  • Provenance and peer review Not commissioned; externally peer reviewed by Joshua Klein, Boston, USA.

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