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Diabetic amyotrophy: a painful radiculoplexus neuropathy
  1. Dafydd Llewelyn1,
  2. J Gareth Llewelyn2
  1. 1 Department of Neurology, University Hospital of Wales, Cardiff, UK
  2. 2 Department of Neurology, Royal Gwent Hospital, Newport, UK
  1. Correspondence to Dr Dafydd Llewelyn, Department of Neurology, University Hospital of Wales, Cardiff, Wales, UK; drdafyddllewelyn{at}gmail.com

Abstract

Diabetic lumbosacral radiculoplexus neuropathy is a monophasic syndrome of diffuse pain and weakness that typically affects the lower limbs asymmetrically and is often associated with significant weight loss. Recovery can be prolonged and unpredictable. It is a clinical diagnosis and investigations are performed mainly to exclude other causes. Although it is most likely caused by a microvasculitis, there is no evidence to support using intravenous immunoglobulin or any long-term immunosuppression. Pulsed methylprednisolone may help pain if given within 2–3 months of symptom onset.

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Footnotes

  • Contributors Both authors contributed equally.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Competing interests None declared.

  • Patient consent Not required.

  • Provenance and peer review Commissioned; externally peer reviewed by Haider Katifi, Southampton, UK.

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