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Multiple system atrophy mimicked by multi-organ pathology
  1. Sana Khan1,
  2. Gnanamurthy Sivakumar2,
  3. Stuart Currie3,
  4. Jane Alty4
  1. 1 School of Medicine, University of Leeds, Leeds, UK
  2. 2 Department of Neurosurgery, Leeds Teaching Hospitals NHS Trust, Leeds, UK
  3. 3 Department of Neuroradiology, Leeds Teaching Hospitals NHS Trust, Leeds, UK
  4. 4 Department of Neurology, Leeds Teaching Hospitals NHS Trust, Leeds, UK
  1. Correspondence to Dr Jane Alty, Department of Neurology, Leeds Teaching Hospitals NHS Trust, Leeds LS1 3EX, UK; jane.alty{at}


Both multiple system atrophy and Parkinson’s disease may present with parkinsonism and autonomic dysfunction. We describe a patient who initially met the diagnostic criteria for multiple system atrophy and had atypical features for Parkinson’s disease including blackouts and pyramidal signs. Ultimately, he was found to have three separate diagnoses rather than a single unifying one.

  • clinical neurology
  • Parkinson's disease
  • Autonomic
  • Spinal tumour
  • multiple system atrophy

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  • Twitter @janealty1

  • Contributors SK wrote the first draft, contributed to revisions and obtained consent; JA conceived the idea and contributed to revisions; GS contributed to revisions; SC wrote figure legends and provided formatted images.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Competing interests JA has previously been awarded grants by Parkinson’s UK, Ipsen, UCB Foundation, Merz, Medtronic, Bial and AbbVie; received honoraria from Allergan and Medical Update Ltd and been on expert advisory boards for Merz and AbbVie. She has stock ownership in Clear Sky Diagnostics. She receives royalties from Taylor & Francis Group for medical textbooks she has coauthored.

  • Patient consent for publication Obtained

  • Provenance and peer review Not commissioned. Externally peer reviewed by Donald Grosset, Glasgow, UK.

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  • Editors’ commentary
    Phil E M Smith Geraint N Fuller

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