You are here

Article Text

Article menu
Download PDFPDF
Image of the moment
Central pontine (and extrapontine) myelinolysis despite appropriate sodium correction
  1. Andrew Micieli1,
  2. Umberin Najeeb2,
  3. William Kingston1
  1. 1 Division of Neurology, Department of Medicine, University of Toronto, Toronto, Ontario, Canada
  2. 2 Department of Medicine, University of Toronto, Faculty of Medicine, Toronto, Ontario, Canada
  1. Correspondence to Dr Andrew Micieli, Neurology, University of Toronto Faculty of Medicine, Toronto, ON M5S 1A8, Canada; andrew.micieli{at}mail.utoronto.ca

https://doi.org/10.1136/practneurol-2019-002347

Statistics from Altmetric.com

    Request Permissions

    If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.

    A 55-year-old woman presented to the emergency department with generalised weakness and lightheadedness. She had a history of depression, hypertension, coeliac disease and excessive alcohol use. There were no focal neurological symptoms/signs. Abnormal laboratory results included serum sodium of 99 mmol/L, potassium of 3.0 mmol/L, serum osmolality of 214 mmol/kg, urine sodium of 32 mmol/L and urine osmolality of 630 mmol/kg. We suspected that her hyponatraemia was multifactorial, with contribution from escitalopram, hydrochlorothiazide, diuretic use and excessive alcohol intake. Further investigations found no evidence of primary hyperaldosteronism, adrenal insufficiency, hypothyroidism …

    View Full Text

    Footnotes

    • Contributors AM: involved in conception, writing and editing the manuscript. UN: involved in writing and editing the manuscript. WK: involved in conception, writing and editing the manuscript.

    • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

    • Competing interests None declared.

    • Patient consent for publication Obtained.

    • Provenance and peer review Not commissioned; externally peer reviewed by Martin Duddy, Newcastle-upon-Tyne, UK.

    Other content recommended for you