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Coeliac disease presenting with chorea
  1. Stela Lefter1,
  2. Luke Corcoran2,
  3. Eimear McAuliffe2,
  4. Rahim Khan3,
  5. Louise Burke4,
  6. Michael Regan2,
  7. Marios Hadjivassiliou5
  1. 1 Neurology, Cork University Hospital Group, Cork, Ireland
  2. 2 Cork University Hospital Group, Cork, Ireland
  3. 3 Gastroenterology, Cork University Hospital Group, Cork, Ireland
  4. 4 Pathology, Cork University Hospital Group, Cork, Ireland
  5. 5 Royal Hallamshire Hospital, Sheffield, UK
  1. Correspondence to Dr Stela Lefter, Neurology, Cork University Hospital Group, Cork, T12 H2FD, Ireland; stela_lefter{at}


Chorea can be genetic or acquired, and often leads to a challenging diagnostic conundrum. In a significant proportion, there is no specific identifiable cause. Chorea is a rare but potentially reversible neurological manifestation of coeliac disease, usually presenting insidiously and often presumed to be associated with typical gastrointestinal symptoms. We report a patient with rapidly progressive generalised chorea, but without preceding gastrointestinal symptoms, who was subsequently diagnosed with coeliac disease. A gluten-free diet resulted in complete resolution of the chorea.

  • chorea
  • coeliac disease
  • neuroimmunology

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  • Contributors SL, MR and MH designed and conceptualised the study, analysed the data and drafted the manuscript for intellectual content. LC, EM, RK and LB had a major role in the data acquisition, analysis and interpretation. All the authors revised the manuscript, and read and approved the final version.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Competing interests None declared.

  • Patient consent for publication Obtained.

  • Provenance and peer review Not commissioned. Externally peer-reviewed by Mirdhu Wickremaratchi, Sussex, UK, and Mayke Oosterloo, Maastricht, the Netherlands.

  • Data availability statement All data relevant to the study are included in the article or uploaded as supplementary information.

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