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Seeding of infection in previously asymptomatic meningioma
  1. Edward Christopher1,2,
  2. Fiona C Moreton2,
  3. Antonia Torgersen2,
  4. Peter Foley1,2
  1. 1College of Medicine and Veterinary Medicine, The University of Edinburgh, Edinburgh, UK
  2. 2Department of Clinical Neurosciences, Western General Hospital, Edinburgh, UK
  1. Correspondence to Edward Christopher, College of Medicine and Veterinary Medicine, The University of Edinburgh, Edinburgh EH8 9YL, UK; edward.christopher{at}

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Case history

A 75-year-old woman, who was recovering from a recent episode of urosepsis, presented with 3 days of recurrent focal motor seizures affecting the right arm. She was aware and orientated throughout each episode but experienced confusion and weakness afterwards. On examination, she had mild pyramidal weakness of the right arm. CT scan of head showed no acute abnormality. She was started on levetiracetam. Her history included type 2 diabetes mellitus, posterior circulation stroke, and known asymptomatic meningiomas at the left frontal lobe and left parietal lobe. She had no personal or family history of seizures.

Her seizures became more frequent despite rapid titration of levetiracetam, with later addition of sodium valproate and phenytoin. Five days later, her condition rapidly decompensated and progressed into generalised convulsive status epilepticus, refractory to lorazepam, phenytoin, sodium valproate, levetiracetam and midazolam. She was transferred to the …

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  • Contributors All authors satisfy the ICMJE criteria for authorship.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Competing interests None declared.

  • Patient consent for publication Obtained.

  • Provenance and peer review Not commissioned; externally peer reviewed by Ravi Nannapaneni, Cardiff, UK.

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