Article Text
PDFWhat neurologists need to understand outside their own speciality
Ammonia: what adult neurologists need to know
Abstract
Hyperammonaemia is often encountered in acute neurology and can be the cause of acute or chronic neurological symptoms. Patients with hyperammonaemia may present with seizures or encephalopathy, or may be entirely asymptomatic. The underlying causes are diverse but often straightforward to diagnose, although sometimes require specialist investigations. Haemodialysis or haemo(dia)filtration is the first-line treatment for acute severe hyperammonaemia (of any cause) in an adult. Here we discuss our approach to adult patients with hyperammonaemia identified by a neurologist.
- Coma
- epilepsy
- metabolic disease
Statistics from Altmetric.com
Linked Articles
- Editors’ commentary
- Miscellaneous
Read the full text or download the PDF:
Other content recommended for you
- How to use serum ammonia
- Recurrent vomiting and lethargy in an infant—just another viral illness?
- Hyperammonaemic encephalopathy after initiation of valproate therapy in unrecognised ornithine transcarbamylase deficiency
- Status epilepticus secondary to hyperammonaemia: a late presentation of an undiagnosed urea cycle defect
- Drug-induced hyperammonaemia
- Prenatal benzoate treatment in urea cycle defects
- Valproate-induced fatal acute hyperammonaemia-related encephalopathy in late-onset ornithine transcarbamylase deficiency
- Non-hepatic hyperammonaemia: an important, potentially reversible cause of encephalopathy
- Ornithine carbamoyltransferase deficiency
- Late-onset ornithine transcarbamylase deficiency mimicking a focal opercular syndrome