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Menière’s disease
  1. Mansur Amirovich Kutlubaev1,
  2. Ilmari Pyykko2,
  3. Todd A Hardy3,
  4. Robert Gürkov4
  1. 1 Department of Neurology, Bashkir State Medical University, Ufa, Russian Federation
  2. 2 Hearing and Balance Research Unit, Field of Otolaryngology, School of Medicine, Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland
  3. 3 Brain and Mind Centre, The University of Sydney, Sydney, Australia
  4. 4 Department of Otorhinolaryngology Head and Neck Surgery, Klinikum Bielefeld, Bielefeld, Germany


Menière’s disease causes paroxysmal rotatory vertigo, due to endolymphatic hydrops, an accumulation of endolymph in the endolymphatic space of the labyrinth. Its major symptoms are attacks of rotatory vertigo lasting minutes to hours, with unilateral hearing loss, tinnitus and aural fullness. As the disease progresses, attacks happen less often, but hearing loss and tinnitus gradually become permanent. Neuro-otological complications may develop, such as benign paroxysmal positional vertigo, vestibular drop attacks and bilateral vestibulopathy. The diagnosis of Menière’s disease is based on the typical clinical picture and typical findings on the audiogram. Furthermore, it is now possible to diagnose it by MR of the inner ear. Long-term management has several steps, including diet, diuretics, intratympanic injection of corticosteroid or gentamicin and surgery (endolymphatic sac surgery, grommet insertion, surgical labyrinthectomy).

  • Vertigo
  • Neurootology
  • ENT

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  • Contributors MAK prepared the first draft. IP, TH and RG reviewed the manuscript for intellectual content.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Competing interests MAK reports signing contracts to receive fees for lectures with Abbot Laboratories.

  • Patient consent for publication Not required.

  • Provenance and peer review Commissioned. Externally peer reviewed by Diego Kaski, London, UK.

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  • Editors’ commentary
    Phil E M Smith Geraint N Fuller

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