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Unilateral meningitis: unusual central nervous system involvement in rheumatoid arthritis
  1. Carla Tortorella1,
  2. Luca Prosperini1,
  3. Giandomenico Sebastiani2,
  4. Claudio Gasperini1
  1. 1 Department of Neurosciences, San Camillo Forlanini Hospital, Roma, Italy
  2. 2 UOC of Rheumatology, San Camillo Forlanini Hospital, Roma, Italy
  1. Correspondence to Carla Tortorella, Department of Neurosciences, S. Camillo Forlanini Hospital, Circonvallazione Gianicolense, Rome 87-00152, Italy; carla.tortorella{at}

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A 40-year-old woman developed acute onset of right-sided weakness with ipsilateral partial motor seizures. She had a 6-month history of well-controlled rheumatoid arthritis treated with certolizumab (a biological pegylated tumour necrosis factor (TNF)-α inhibitors). MR scan of brain showed diffusion-weighted imaging (DWI) and fluid-attenuated inversion recovery (FLAIR) hyperintensity of the left fronto-parietal cortex without apparent diffusion coefficient (ADC) signal restriction and left-sided …

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  • Contributors CT and CG: writing and editing the paper. CT, LP, CG and GS discussing the case and reviewing the paper.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Competing interests None declared.

  • Patient consent for publication Consent obtained directly from patient(s).

  • Provenance and peer review Not commissioned; externally peer reviewed by Gillian Ingram, Swansea, UK.

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