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A 52-year-old man presented with acute onset of primarily anterograde amnesia. He had a history of diabetes mellitus, coronary artery disease and smoking. We found no other focal neurological deficits. The amnesia improved slowly over the subsequent weeks.
MR scan of the brain showed moderate chronic microangiopathic white matter changes and acute infarction in both fornices (figure 1). This most likely explained the abrupt onset of anterograde amnesia and prolonged recovery.
Anatomy and function
The fornices are white matter tract bundles that lie on the medial aspects of the cerebral hemispheres. They each contain output fibres arising …
Contributors All authors contributed to the conception of the manuscript. MS and HR contributed to the design of the manuscript, editing the manuscript and review of the relevant literature. LH interpreted the neuroimaging studies and supplied the relevant images.
Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.
Competing interests None declared.
Provenance and peer review Not commissioned. Externally peer reviewed by Thomas Miller, London, UK.