Statistics from Altmetric.com
If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.
A 52-year-old man was brought to the emergency department by a family member with concern regarding a change in his behaviour. Over the preceding days, he had become vague and lethargic, and at times paranoid. There were no other reported neurological or systemic symptoms at first presentation. He had a history of hearing loss starting in his 20s, and diabetes diagnosed in his 30s but no personal or family history of neurological disease.
He was of slight build. He was initially alert and orientated but slow to answer questions and had a subtle left-sided weakness. Routine bedside observations and blood glucose were normal.
CT scan of the brain showed bilateral temporal lobe low density consistent with vasogenic oedema with associated mass effect and loss …
Contributors All of the listed authors were involved in the production of this manuscript.
Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.
Competing interests None declared.
Provenance and peer review Not commissioned; externally peer reviewed by Rhys Thomas, Newcastle-upon-Tyne, UK.
Read the full text or download the PDF:
Other content recommended for you
- Cortical abnormalities on MRI: what a neurologist should know
- Mitochondrial myopathy, encephalopathy, lactic acidosis and stroke-like episodes: an important cause of stroke in young people
- Uncommon mutation in mitochondrial encephalomyopathy, lactic acidosis and stroke-like episodes (MELAS)
- MELAS: a new disease associated mitochondrial DNA mutation and evidence for further genetic heterogeneity
- A cause of encephalopathy not to be missed
- MERRF/MELAS overlap syndrome: a double pathogenic mutation in mitochondrial tRNA genes
- Multiple presentation of mitochondrial disorders
- Mitochondrial disease: mimics and chameleons
- Infectious encephalitis: mimics and chameleons
- Immunohistochemical analysis of the oxidative phosphorylation complexes in skeletal muscle from patients with mitochondrial DNA encoded tRNA gene defects