Article Text

Download PDFPDF
Radiological clues to a mitochondrial problem
  1. Jonathan Hawken1,
  2. Paul Tobin1,
  3. Mo Hu1,
  4. Marc Edwards1,
  5. Srinivasa Abburu2,
  6. William Owen Pickrell1,3
  1. 1 Neurology Department, Swansea Bay University Health Board, Swansea, UK
  2. 2 Radiology Department, Swansea Bay University Health Board, Swansea, UK
  3. 3 Swansea University Medical School, Swansea, UK
  1. Correspondence to Dr Jonathan Hawken, Neurology Department, Swansea Bay University Health Board, Swansea, UK; drhawken{at}

Statistics from

Request Permissions

If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.

A 52-year-old man was brought to the emergency department by a family member with concern regarding a change in his behaviour. Over the preceding days, he had become vague and lethargic, and at times paranoid. There were no other reported neurological or systemic symptoms at first presentation. He had a history of hearing loss starting in his 20s, and diabetes diagnosed in his 30s but no personal or family history of neurological disease.

He was of slight build. He was initially alert and orientated but slow to answer questions and had a subtle left-sided weakness. Routine bedside observations and blood glucose were normal.

CT scan of the brain showed bilateral temporal lobe low density consistent with vasogenic oedema with associated mass effect and loss …

View Full Text


  • Contributors All of the listed authors were involved in the production of this manuscript.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Competing interests None declared.

  • Provenance and peer review Not commissioned; externally peer reviewed by Rhys Thomas, Newcastle-upon-Tyne, UK.

Other content recommended for you