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Rapid recovery of EEG changes in severe hepatic encephalopathy following liver transplantation
  1. Pia De Stefano1,2,
  2. Hervé Quintard1,
  3. Nils Siegenthaler1,
  4. Margitta Seeck2,
  5. Fabienne Picard2
  1. 1 Intensive Care Unit, Department of Intensive Care, Geneva University Hospitals, Geneva, Switzerland
  2. 2 EEG and Epilepsy Unit, Neurology Unit, Department of Clinical Neurosciences, Geneva University Hospitals, Geneva, Switzerland
  1. Correspondence to Dr Pia De Stefano, Department of Clinical Neurosciences, Geneva University Hospitals, Geneva, Switzerland; pia.destefano{at}

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A 45-year-old woman with fulminant hepatitis B was admitted to the intensive care unit. She went into coma within 2 days and her electroencephalogram (EEG) without sedation showed changes of severe encephalopathy with an unreactive burst-suppression background, and with generalised periodic discharges with triphasic morphology (figure 1) during bursts1. She underwent liver transplantation and EEG 3 days later showed changes of a mild encephalopathy with reactive theta background (figure 2). She made an excellent clinical …

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  • Contributors PDS: methodology, formal analysis, investigation, data curation, writing original draft and visualisation. HQ: supervision, project administration, investigation and editing. NS: conceptualisation, investigation and editing. MS: supervision. FP: supervision, formal analysis, investigation, data curation writing and editing.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Competing interests MS is shareholder of Epilog NV and received speaker's fees from Philips and Desitin.

  • Provenance and peer review Not commissioned. Externally peer reviewed by Nick Kane, Bristol, UK, and Jacquie Deeb, Romford, UK.

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