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What neurologists need to understand outside their own speciality
Fertility treatment for people with epilepsy
  1. Ginette Moores1,
  2. Kimberly Liu2,
  3. Aleksandra Pikula1,3,
  4. Esther Bui1
  1. 1 Division of Neurology, Department of Medicine, University of Toronto, Toronto, Ontario, Canada
  2. 2 Department of Obstetrics and Gynecology, University of Toronto, Toronto, Ontario, Canada
  3. 3 Krembil Brain Institute, University Health Network, Toronto, Ontario, Canada
  1. Correspondence to Dr Ginette Moores, Division of Neurology, Department of Medicine, University of Toronto, Toronto, Canada; ginette.moores{at}medportal.ca

Abstract

Fertility treatment, including assisted reproductive technology (ART), is increasingly used. Sex hormones influence seizure control as well as interacting with antiseizure medications, and so the hormonal manipulation involved in fertility treatments has direct implications for people with epilepsy. Here, we summarise the various fertility treatments and consider their important influences on epilepsy care. While early observations raised concerns about seizure exacerbation associated with ART, there are limited data to guide best practice in people with epilepsy, and further research is needed.

  • EPILEPSY

Data availability statement

All data relevant to the study are included in the article.

https://doi.org/10.1136/pn-2023-003922

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    Data availability statement

    All data relevant to the study are included in the article.

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    Footnotes

    • X @ggmoores

    • Contributors EB and GM conceptualised and initiated the work. GM, KL and EB advised on content and wrote the first drafts of the paper. GM, KL, AP and EB revised the draft paper. All authors were involved in the response to reviewers and approved the final version of the paper.

    • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

    • Competing interests None declared.

    • Provenance and peer review Not commissioned; externally peer reviewed by Tamara Kaplan, Boston, USA, and Ruth Dobson, London, UK.

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