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Functional vitamin B12 deficiency
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  • Published on:
    Clinical signs and symptoms emphasized.

    Dear Editor,

    I wish to commend the authors for their paper on functional vitamin B12 deficiency.

    It is important that despite the array of investigative tools that may be available at the disposal of clinicians, clinical signs and symptoms are given their due emphasis particularly in Vitamin B12 deficiency. The authors report a case where the serum cobalamin was normal in the face of anaemia and neurol...

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    Conflict of Interest:
    None declared.
  • Published on:
    "Functional" Vitamin B12 Deficiency

    Dear Editor,

    I read with interest the important case report of Turner and Talbot describing clinical subacute combined degeneration in a patient with “functional” vitamin B12 deficiency (defined by elevated levels of the B12 -dependent metabolites, methylmalonic acid and homocysteine, despite normal serum B12 values).1 It is important to note that although their patient did not improve with hydroxycobalamin the...

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    Conflict of Interest:
    None declared.

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