Article Text

other Versions

Severe MRI-visible perivascular spaces due to cerebral amyloid angiopathy
  1. Sayan Datta1,
  2. Hawraman Ramadan1,
  3. David J Werring2
  1. 1Department of Neurology, Bradford Royal Infirmary, Bradford, UK
  2. 2Stroke Research Group, Department of Brain Repair and Rehabilitation, UCL Institute of Neurology, London WC1N 3BG, UK
  1. Correspondence to Dr Hawraman Ramadan, Department of Neurology, Bradford Teaching Hospitals NHS Trust, Duckworth lane, Bradford Bd6 6 RJ, UK; Hawraman.Ramadan{at}

Statistics from


MRI-visible perivascular spaces are a recently recognised neuroimaging marker of cerebral small vessel diseases1 and centrum semiovale MRI-visible perivascular spaces may be a neuroimaging marker of cerebral amyloid angiopathy.2

We report an elderly woman with speech and memory disturbance, whose MR scan of brain showed severe centrum semiovale perivascular spaces. Subsequent MRI with blood-sensitive sequences showed multiple cerebral microbleeds, consistent with probable cerebral amyloid angiopathy. Dilated perivascular spaces can be a marker of cerebral amyloid angiopathy. Their recognition may change clinical management, since current recommendations for cerebral amyloid angiopathy treatment involve avoiding antithrombotic drugs and emphasising hypertensive control.

Case report

A previously healthy 81-year-old woman gave a 3-month history …

View Full Text

Request Permissions

If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.

Linked Articles

  • Editors' commentary
    Phil Smith Geraint Fuller