Article Text
Abstract
Postural tachycardia syndrome (POTS) is a multifactorial clinical syndrome defined by an increase in heart rate of ≥30 bpm on standing from supine position (or ≥40 bpm in children). It is associated with symptoms of cerebral hypoperfusion that are worse when upright and improve when in supine position. Patients often have additional symptoms including severe fatigue and difficulty concentrating. There are several possible pathophysiologic mechanisms including hypovolaemia, small-fibre peripheral neuropathy and hyperadrenergic states. POTS can also be associated with several disorders including mastocytosis, Ehlers-Danlos syndrome (hypermobility type) and autoimmune disorders. The treatment is focused on symptom relief and not solely on reducing tachycardia. Given its varying presentations, it is important to employ a practical, mechanism-focused approach to the diagnosis and management of POTS.
- postural tachycardia syndrome
- POTS
- tachycardia
- orthostatic intolerance
- AUTONOMIC
Statistics from Altmetric.com
Linked Articles
- Editors' commentary
Read the full text or download the PDF:
Other content recommended for you
- Cardiac neurotransmission imaging with 123I-meta-iodobenzylguanidine in postural tachycardia syndrome
- Autonomic function testing: an important diagnostic test for patients with syncope
- Psychiatric profile and attention deficits in postural tachycardia syndrome
- Is ivabradine a wonder drug for atypical POTS?
- Postural orthostatic tachycardia syndrome in primary care: diagnosis, treatment and a case of African-American man presenting with POTS
- Improvement of hyperadrenergic postural orthostatic tachycardia syndrome (POTS) with methylated B vitamins in the setting of a heterozygous COMT Val158Met polymorphism
- Bupropion in the treatment of postural orthostatic tachycardia syndrome (POTS): a single-center experience
- Neurogenic orthostatic hypotension: chasing “the fall”
- Successful treatment of postural orthostatic tachycardia and mast cell activation syndromes using naltrexone, immunoglobulin and antibiotic treatment
- Postural tachycardia syndrome is associated with significant symptoms and functional impairment predominantly affecting young women: a UK perspective