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Vagus nerve stimulation for epilepsy
  1. John Duncan
  1. Institute of Neurology, UCL, London, London, UK
  1. Correspondence to Prof John Duncan, Institute of Neurology, UCL, London WC1N 3BG, UK; j.duncan{at}

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Refractory epilepsy causes physical, psychological, psychiatric and social morbidities and carries an increased risk of premature mortality. Resective neurosurgery brings the possibility of long-term seizure remission in those with focal epilepsy, but is only suitable in approximately half of the patients who undergo presurgical evaluation,1 either because a single epileptogenic zone is not definable or resection would compromise eloquent cortex.

The clinical use of vagus nerve stimulation (VNS) was first described in 1990 and as described by Pérez-Carbonell in this issue of Practical Neurology has …

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  • Contributors I wrote the article myself.

  • Funding This study was funded by National Institute for Health Research (

  • Competing interests None declared.

  • Patient consent for publication Not required.

  • Provenance and peer review Commissioned; internally peer reviewed.

Linked Articles

  • Review
    Laura Pérez-Carbonell Howard Faulkner Sean Higgins Michalis Koutroumanidis Guy Leschziner

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