Article Text

other Versions

Download PDFPDF
Persisting brain inflammation: a neurological whodunnit
  1. Marija Cauchi1,
  2. Paul Reading2,
  3. Neil P Robertson1,
  4. Stephen Jolles3,
  5. Richard Davenport4
  1. 1Division of Psychological Medicine and Clinical Neurosciences, Cardiff University, Cardiff, UK
  2. 2Department of Neurology, James Cook University Hospital, Middlesbrough, UK
  3. 3Immunodeficiency Centre for Wales, University Hospital of Wales, University Hospital of Wales, Cardiff, UK
  4. 4Department of Clinical Neurosciences, Royal Hospital for Children and Young People and Clinical Neurosciences, Royal Infirmary of Edinburgh, Edinburgh, UK
  1. Correspondence to Dr Marija Cauchi, Cardiff University Division of Psychological Medicine and Clinical Neurosciences, Cardiff, UK; cauchim1{at}


A woman in her 30s presented with vertigo, nausea and vomiting followed by diplopia and cerebellar signs. This was on the background of a complex previous medical history of autoimmune diseases and recurrent infections. The differential diagnoses of multiple sclerosis, neuromyelitis optica, sarcoidosis and multiple vasculitides are considered. We discuss a rare condition that can present to adult neurologists with neurological involvement. This case was presented at the Association of British Neurologists Virtual Meeting 2021 as a Clinicopathological Conference.

  • neurogenetics
  • clinical neurology
  • neuroimmunology

Statistics from

Request Permissions

If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.


  • Contributors MC: initial draft, manuscript revisions. PR: case discussant, manuscript revision. NPR, SJ: manuscript revision. RD: overall concept, manuscript revisions.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Competing interests None declared.

  • Provenance and peer review Commissioned; externally peer reviewed by Neil Scolding, Bristol, UK.

Other content recommended for you