Article Text

Download PDFPDF
Management of carotid atherosclerosis in stroke


Internal carotid artery atherosclerosis is a major risk factor for stroke, accounting for 15–20% of ischaemic strokes. Revascularisation procedures—either carotid endarterectomy or carotid artery stenting—can reduce the risk of stroke for those with significant (>50%) luminal stenosis but particularly for those with more severe (70–99%) stenosis. However, advances in medical pharmacotherapy have implications for the relative benefit from surgery for symptomatic carotid atherosclerosis, as well as our approach to asymptomatic disease. This review considers the evidence underpinning the current medical and surgical management of symptomatic carotid atherosclerosis, the importance of factors beyond the degree of luminal stenosis, and developments in therapeutic strategies. We also discuss the importance of non-stenotic but high-risk carotid atherosclerotic plaques on the cause of stroke, and their implications for clinical practice.


Data availability statement

No data are available.

Statistics from

Request Permissions

If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.

Other content recommended for you