RT Journal Article SR Electronic T1 The opsoclonus–myoclonus syndrome JF Practical Neurology JO Pract Neurol FD BMJ Publishing Group Ltd SP 160 OP 166 DO 10.1136/practneurol-2011-000017 VO 11 IS 3 A1 Jitendra Kumar Sahu A1 Kameshwar Prasad YR 2011 UL http://pn.bmj.com/content/11/3/160.abstract AB The opsoclonus–myoclonus syndrome is a rare and distinct neurological disorder characterised by rapid multidirectional conjugate eye movements (opsoclonus), myoclonus and ataxia, along with behavioural changes in adults and irritability in children. Sometimes it is due to a self-limiting presumed para-infectious brainstem encephalitis but it may also represent a non-metastatic manifestation of neuroblastoma in children and small cell carcinoma of the lung in adults. In this article, we will describe the clinical features, diagnosis, pathogenesis and management.