RT Journal Article SR Electronic T1 When the patient fails to respond to treatment: TIAs that go on, and on JF Practical Neurology JO Pract Neurol FD BMJ Publishing Group Ltd SP 103 OP 111 DO 10.1136/jnnp.2007.139378 VO 8 IS 2 A1 G J Hankey YR 2008 UL http://pn.bmj.com/content/8/2/103.abstract AB Most transient ischaemic attacks (TIAs) stop, with or without treatment, but some are followed by stroke within days or longer. But if the TIAs do not stop then the diagnosis must be reviewed (are they really TIAs or could they be migraine or epilepsy?), and if they are TIAs, what are they caused by (atherothromboembolism, embolism from the heart, etc)? With this information, both the medical and any surgical treatment can be optimised, even though one must accept that the randomised controlled trials mostly have not addressed the particular issue of continuing TIAs.