PT - JOURNAL ARTICLE AU - Rustam Al-Shahi AU - Neil J. Scolding AU - Jeanne E. Bell AU - Adam Z. Zeman AU - Charles P. Warlow TI - A Young Man with a Fatal Encephalopathy AID - 10.1046/j.1474-7766.2002.00304.x DP - 2002 Feb 01 TA - Practical Neurology PG - 26--35 VI - 2 IP - 1 4099 - http://pn.bmj.com/content/2/1/26.short 4100 - http://pn.bmj.com/content/2/1/26.full SO - Pract Neurol2002 Feb 01; 2 AB - CASE PRESENTATION History In early 1999, a right-handed manufacturing engineer in his thirties presented to his general practitioner (GP) with a week-long history of diminished sensation and paraesthesiae affecting his left arm and leg. Two months prior to presentation he had contracted a ‘flu-like illness that had left him with persistent fatigue. At presentation, his GP noticed weakness of his left hand and made a presumptive diagnosis of multiple sclerosis. He prescribed a five-day course of oral prednisolone 40 mg daily, which the patient took for only one day, making a transient improvement. The next day he had difficulty making decisions at work and was stopped by the police for speeding in a residential area. Two weeks after the onset of his neurological symptoms, he was admitted to a local hospital with confusion and then transferred to the Neurology department in Edinburgh the following day.Two years beforehand, in 1997