PT - JOURNAL ARTICLE AU - Winer, J B TI - When the Guillain-Barré patient fails to respond to treatment AID - 10.1136/jnnp.2009.176578 DP - 2009 Aug 01 TA - Practical Neurology PG - 227--230 VI - 9 IP - 4 4099 - http://pn.bmj.com/content/9/4/227.short 4100 - http://pn.bmj.com/content/9/4/227.full SO - Pract Neurol2009 Aug 01; 9 AB - Most patients with Guillain-Barré syndrome (GBS) respond to treatment with intravenous immunoglobulin, but it is not uncommon for some to continue to deteriorate for a period after treatment has been started. This may reflect the natural history of the disease, or an error in diagnosis. This article reflects my own view of what to do in this situation, with a review of what few data there are to guide decision making.