RT Journal Article SR Electronic T1 The Persistent Vegetative State: Conscious of Nothing? JF Practical Neurology JO Pract Neurol FD BMJ Publishing Group Ltd SP 214 OP 217 DO 10.1046/j.1474-7766.2002.00069.x VO 2 IS 4 A1 Adam Zeman YR 2002 UL http://pn.bmj.com/content/2/4/214.abstract AB The persistent vegetative state (PVS) was described in the Lancet exactly 30 years ago by Bryan Jennett, a neurosurgeon, and the neurologist Fred Plum (Jennett & Plum 1972). Jennett has recently reviewed the subject (Jennett 2002). Sometimes described as a condition of wakefulness without awareness, it can follow a range of severe insults to the brain. Often misdiagnosed, frequently misunderstood, the syndrome provides a useful shorthand for a diverse but distinctive set of clinical phenomena. Although it has withstood the scrutiny of ethicists and lawyers, it assumes a concept of awareness that may not stand the test of time. In this article I will sketch its key features and end by asking how confident we can really be that a patient in the PVS is wakeful, but conscious of nothing.Many of us will remember our first encounter with a patient in the vegetative state (VS), as the condition is