TY - JOUR T1 - Disease modification in multiple sclerosis: an update JF - Practical Neurology JO - Pract Neurol SP - 6 LP - 13 DO - 10.1136/practneurol-2013-000601 VL - 14 IS - 1 AU - Claire M Rice Y1 - 2014/02/01 UR - http://pn.bmj.com/content/14/1/6.abstract N2 - Although there has been unequivocal progress in the development of treatments for multiple sclerosis over the last 20 years, currently licensed treatments have demonstrated convincing effects on disease course only with reference to relapse frequency. This review summarises the progress made, highlights the indications for, and limitations of, current disease-modifying therapies and discusses some interventions currently in development. ER -