%0 Journal Article %A Antoniya Todorova %A Peter Jenner %A K Ray Chaudhuri %T Non-motor Parkinson's: integral to motor Parkinson's, yet often neglected %D 2014 %R 10.1136/practneurol-2013-000741 %J Practical Neurology %P 310-322 %V 14 %N 5 %X Non-motor symptoms are a key component of Parkinson's disease, possibly representing a clinical biomarker of its premotor phase. The burden of non-motor symptoms can define a patient's health-related quality of life. Non-motor symptoms substantially increase the cost of care—requiring increased hospitalisation and treatment—and pose a major challenge to healthcare professionals. However, clinicians often regard non-motor symptoms and their management as peripheral to that of the motor symptoms. Here, we address the clinical issues and unmet needs of non-motor symptoms in Parkinson's disease. %U https://pn.bmj.com/content/practneurol/14/5/310.full.pdf