PT - JOURNAL ARTICLE AU - Antoniya Todorova AU - Peter Jenner AU - K Ray Chaudhuri TI - Non-motor Parkinson's: integral to motor Parkinson's, yet often neglected AID - 10.1136/practneurol-2013-000741 DP - 2014 Oct 01 TA - Practical Neurology PG - 310--322 VI - 14 IP - 5 4099 - http://pn.bmj.com/content/14/5/310.short 4100 - http://pn.bmj.com/content/14/5/310.full SO - Pract Neurol2014 Oct 01; 14 AB - Non-motor symptoms are a key component of Parkinson's disease, possibly representing a clinical biomarker of its premotor phase. The burden of non-motor symptoms can define a patient's health-related quality of life. Non-motor symptoms substantially increase the cost of care—requiring increased hospitalisation and treatment—and pose a major challenge to healthcare professionals. However, clinicians often regard non-motor symptoms and their management as peripheral to that of the motor symptoms. Here, we address the clinical issues and unmet needs of non-motor symptoms in Parkinson's disease.