RT Journal Article SR Electronic T1 Non-motor Parkinson's: integral to motor Parkinson's, yet often neglected JF Practical Neurology JO Pract Neurol FD BMJ Publishing Group Ltd SP 310 OP 322 DO 10.1136/practneurol-2013-000741 VO 14 IS 5 A1 Antoniya Todorova A1 Peter Jenner A1 K Ray Chaudhuri YR 2014 UL http://pn.bmj.com/content/14/5/310.abstract AB Non-motor symptoms are a key component of Parkinson's disease, possibly representing a clinical biomarker of its premotor phase. The burden of non-motor symptoms can define a patient's health-related quality of life. Non-motor symptoms substantially increase the cost of care—requiring increased hospitalisation and treatment—and pose a major challenge to healthcare professionals. However, clinicians often regard non-motor symptoms and their management as peripheral to that of the motor symptoms. Here, we address the clinical issues and unmet needs of non-motor symptoms in Parkinson's disease.