PT  - JOURNAL ARTICLE
AU  - Dani, Krishna A
AU  - Murray, Lesley J
AU  - Razvi, Saif
TI  - Rare neurological diseases: a practical approach to management
AID  - 10.1136/practneurol-2012-000379
DP  - 2013 Aug 01
TA  - Practical Neurology
PG  - 219--227
VI  - 13
IP  - 4
4099  - http://pn.bmj.com/content/13/4/219.short
4100  - http://pn.bmj.com/content/13/4/219.full
SO  - Pract Neurol2013 Aug 01; 13
AB  - Although neurologists are frequently faced with the management of rare diseases, there is little generic guidance for the approach to management. There are complexities with respect to diagnosis, counselling, treatment and monitoring which are idiosyncratic to rare diseases. Here we use a case report as the basis for discussion of the management of rare neurological diseases. We discuss current issues, guidance from regulatory bodies, and offer practical tips for diagnosis, treatment and monitoring, including the use of decision tree analysis. We offer a generic algorithm to aid neurologists when facing rare conditions.