RT Journal Article SR Electronic T1 A practical approach to enlargement of nerves, plexuses and roots JF Practical Neurology JO Pract Neurol FD BMJ Publishing Group Ltd SP 105 OP 115 DO 10.1136/practneurol-2014-001004 VO 15 IS 2 A1 Satish V Khadilkar A1 Rakhil S Yadav A1 Girish Soni YR 2015 UL http://pn.bmj.com/content/15/2/105.abstract AB Detecting enlargement of accessible nerves is very helpful in assessing patients with peripheral nerve disorders, as only a few types of neuropathy lead to nerve thickening. The three leading causes are leprosy, hereditary motor and sensory neuropathies (types 1 and 3) and chronic inflammatory demyelinating neuropathies. MRI, neurography and ultrasonography allow assessment of clinically inaccessible portions of deep-seated nerves, plexuses and roots. As a result, isolated proximal segment thickenings, as found in chronic inflammatory sensory polyradiculopathy, can now be better evaluated and managed. Similarly, focal nerve enlargements due to infection, inflammation, infiltration and neoplasm are being identified and treated effectively. We present a practical approach to the diagnosis and management of patients with enlarged peripheral nerves, plexuses and roots, including cranial nerves.