PT  - JOURNAL ARTICLE
AU  - C M Rice
AU  - T Spencer
AU  - G Bunea
AU  - N J Scolding
AU  - P Sloan
AU  - U Nath
TI  - Intracranial spread of IgG4-related disease via skull base foramina
AID  - 10.1136/practneurol-2015-001315
DP  - 2016 Jun 01
TA  - Practical Neurology
PG  - 240--242
VI  - 16
IP  - 3
4099  - http://pn.bmj.com/content/16/3/240.short
4100  - http://pn.bmj.com/content/16/3/240.full
SO  - Pract Neurol2016 Jun 01; 16
AB  - IgG4-related disease (IgG4-RD) is a newly recognised, multiorgan, inflammatory disease, and its full clinical spectrum remains undefined. We present a biopsy-proven case of IgG4-RD presenting with a parapharyngeal mass with intracranial extension and possible involvement of the brain parenchyma. We highlight the importance of considering the diagnosis in those presenting with tumefactive lesions, leptomeningitis or pachymeningitis and emphasise the value of securing a tissue diagnosis so that appropriate long-term treatment can be instigated and complications avoided.