RT Journal Article
SR Electronic
T1 Intracranial spread of IgG4-related disease via skull base foramina
JF Practical Neurology
JO Pract Neurol
FD BMJ Publishing Group Ltd
SP 240
OP 242
DO 10.1136/practneurol-2015-001315
VO 16
IS 3
A1 C M Rice
A1 T Spencer
A1 G Bunea
A1 N J Scolding
A1 P Sloan
A1 U Nath
YR 2016
UL http://pn.bmj.com/content/16/3/240.abstract
AB IgG4-related disease (IgG4-RD) is a newly recognised, multiorgan, inflammatory disease, and its full clinical spectrum remains undefined. We present a biopsy-proven case of IgG4-RD presenting with a parapharyngeal mass with intracranial extension and possible involvement of the brain parenchyma. We highlight the importance of considering the diagnosis in those presenting with tumefactive lesions, leptomeningitis or pachymeningitis and emphasise the value of securing a tissue diagnosis so that appropriate long-term treatment can be instigated and complications avoided.