RT Journal Article
SR Electronic
T1 Multifocal necrotising leucoencephalopathy following <em>Salmonella</em> infection in an immunocompetent patient
JF Practical Neurology
JO Pract Neurol
FD BMJ Publishing Group Ltd
SP 156
OP 158
DO 10.1136/practneurol-2017-001664
VO 18
IS 2
A1 Michael A O’Gara
A1 Sonali Dharia
A1 David Hilton
A1 Nicholas J Gutowski
YR 2018
UL http://pn.bmj.com/content/18/2/156.abstract
AB Multifocal necrotising leucoencephalopathy is a rare disorder affecting the central nervous system. It is characterised pathologically by microscopic areas of necrosis with pontine predilection but also involvement of extrapontine regions, including the cerebellum, medulla and cerebral hemispheres. It usually occurs on the background of immunosuppression. Here we describe an immunocompetent patient with a recent history of Salmonella infection who presented with subacute neurological deterioration. At postmortem, she had evidence of multifocal necrotising leucoencephalopathy.