RT Journal Article
SR Electronic
T1 AL amyloidosis presenting with limb girdle myopathy
JF Practical Neurology
JO Pract Neurol
FD BMJ Publishing Group Ltd
SP 497
OP 500
DO 10.1136/practneurol-2018-001995
VO 18
IS 6
A1 Naveed Malek
A1 Dominic G O’Donovan
A1 Hadi Manji
YR 2018
UL http://pn.bmj.com/content/18/6/497.abstract
AB An elderly Caucasian man presented with a 10-month history of proximal myopathy and dysphagia. His serum creatine kinase (CK) was elevated at 877 U/L (normal 40–320) and electromyography confirmed a myopathic process. Blood and urine tests suggested myeloma; bone marrow examination showed 30% plasma cells and stained positive for amyloid. The muscle biopsy was initially reported as normal but in the light of the bone marrow report, the biopsy specimen was stained for amyloid, which was positive. We diagnosed systemic amyloidosis causing a myopathy and have started treatment for myeloma.