TY - JOUR T1 - Investigating adults with early-onset epilepsy and intellectual or physical disability JF - Practical Neurology JO - Pract Neurol SP - 115 LP - 130 DO - 10.1136/practneurol-2018-001965 VL - 19 IS - 2 AU - Lina Nashef AU - Rinki Singh AU - Nicholas Moran AU - Elaine Murphy Y1 - 2019/04/01 UR - http://pn.bmj.com/content/19/2/115.abstract N2 - This article focuses on investigating adults with early-onset epilepsy and intellectual or physical disability within adult neurology services. We aim to guide general neurologists in the diagnostic reassessment of people with epilepsy and complex neurological problems of unknown cause. Following an overview, we address imaging, electroencephalography, genetic studies and metabolic testing, and give examples where diagnosis directly influences treatment. Aetiological diagnosis serves to inform prognosis, guide treatment and provide a framework for genetic counselling ER -