TY - JOUR T1 - Grey matter abnormality in progressive multifocal leucoencephalopathy JF - Practical Neurology JO - Pract Neurol SP - 225 LP - 227 DO - 10.1136/practneurol-2020-002852 VL - 21 IS - 3 AU - Christopher Yuki Itoh AU - Han Sung Lee AU - Alan Howe Yee Y1 - 2021/06/01 UR - http://pn.bmj.com/content/21/3/225.abstract N2 - Progressive multifocal leucoencephalopathy (PML) is a demyelinating white matter disease that most often affects immunocompromised people infected by JC virus. The diagnostic gold standard is demonstrable viral DNA or protein from histopathological tissue. However, there are few detailed descriptions of cortical grey matter involvement on neuroimaging. Here we describe the histopathological correlate of cerebral grey matter involvement and radiological accompaniment in a patient with biopsy proven PML. ER -