PT  - JOURNAL ARTICLE
AU  - Yue Hui Lau
AU  - Ahmad Shahir Mawardi
AU  - Norzaini Rose Zain
AU  - Shanthi Viswanathan
TI  - Toluene-induced leukodystrophy from glue sniffing
AID  - 10.1136/practneurol-2021-002942
DP  - 2021 May 26
TA  - Practical Neurology
PG  - practneurol-2021-002942
4099  - http://pn.bmj.com/content/early/2021/05/26/practneurol-2021-002942.short
4100  - http://pn.bmj.com/content/early/2021/05/26/practneurol-2021-002942.full
AB  - A 33-year-old man with a history of chronic toluene abuse through glue sniffing, developed tremors, cerebellar signs and cognitive decline. MR scan of the brain showed global cerebral and cerebellar atrophy with symmetrical T2-weighted hypointensities in the basal ganglia, thalami and midbrain. After stopping glue sniffing, his tremors, ataxia of gait, speech and cognition partially improved. Early recognition and intervention of toluene-induced leukodystrophy could prevent ongoing morbidity and premature mortality.