RT Journal Article
SR Electronic
T1 Toluene-induced leukodystrophy from glue sniffing
JF Practical Neurology
JO Pract Neurol
FD BMJ Publishing Group Ltd
SP practneurol-2021-002942
DO 10.1136/practneurol-2021-002942
A1 Yue Hui Lau
A1 Ahmad Shahir Mawardi
A1 Norzaini Rose Zain
A1 Shanthi Viswanathan
YR 2021
UL http://pn.bmj.com/content/early/2021/05/26/practneurol-2021-002942.abstract
AB A 33-year-old man with a history of chronic toluene abuse through glue sniffing, developed tremors, cerebellar signs and cognitive decline. MR scan of the brain showed global cerebral and cerebellar atrophy with symmetrical T2-weighted hypointensities in the basal ganglia, thalami and midbrain. After stopping glue sniffing, his tremors, ataxia of gait, speech and cognition partially improved. Early recognition and intervention of toluene-induced leukodystrophy could prevent ongoing morbidity and premature mortality.