PT - JOURNAL ARTICLE AU - Su Yin Lim AU - Mohamed Sayed AU - Soma Banerjee AU - Neil Rane AU - Dheeraj Kalladka TI - Young-onset stroke complicating ulcerative colitis AID - 10.1136/practneurol-2021-003106 DP - 2022 Jan 06 TA - Practical Neurology PG - practneurol-2021-003106 4099 - http://pn.bmj.com/content/early/2022/01/06/practneurol-2021-003106.short 4100 - http://pn.bmj.com/content/early/2022/01/06/practneurol-2021-003106.full AB - A 16-year-old girl developed a proximal occlusion of the right middle cerebral artery during a flare-up of acute ulcerative colitis. Although mechanical thrombectomy led to successful middle cerebral artery recanalisation, she required an immediate second thrombectomy due to reocclusion of the same arterial segment. She developed a second ischaemic event 7 days later despite intravenous heparin infusion, later switched to low-molecular-weight heparin, and a third event after 3 days despite the addition of aspirin. We discuss stroke risks in people with inflammatory bowel disease and the uncertainties around anticoagulation and antiplatelet regimens in such cases.