RT Journal Article
SR Electronic
T1 Young-onset stroke complicating ulcerative colitis
JF Practical Neurology
JO Pract Neurol
FD BMJ Publishing Group Ltd
SP practneurol-2021-003106
DO 10.1136/practneurol-2021-003106
A1 Lim, Su Yin
A1 Sayed, Mohamed
A1 Banerjee, Soma
A1 Rane, Neil
A1 Kalladka, Dheeraj
YR 2022
UL http://pn.bmj.com/content/early/2022/01/06/practneurol-2021-003106.abstract
AB A 16-year-old girl developed a proximal occlusion of the right middle cerebral artery during a flare-up of acute ulcerative colitis. Although mechanical thrombectomy led to successful middle cerebral artery recanalisation, she required an immediate second thrombectomy due to reocclusion of the same arterial segment. She developed a second ischaemic event 7 days later despite intravenous heparin infusion, later switched to low-molecular-weight heparin, and a third event after 3 days despite the addition of aspirin. We discuss stroke risks in people with inflammatory bowel disease and the uncertainties around anticoagulation and antiplatelet regimens in such cases.