RT Journal Article SR Electronic T1 Intracranial bruit: Charles Warlow’s challenge revisited JF Practical Neurology JO Pract Neurol FD BMJ Publishing Group Ltd SP 79 OP 81 DO 10.1136/practneurol-2021-003226 VO 22 IS 1 A1 Andrew J Larner YR 2022 UL http://pn.bmj.com/content/22/1/79.abstract AB Over 20 years ago, Charles Warlow, the founding editor of Practical Neurology, offered a copy of his stroke textbook to anyone diagnosing an intracranial arteriovenous malformation by auscultation of the skull alone. This article examines the possible diagnostic value of intracranial bruit in terms of the 2×2 contingency table for diagnostic tests and recounts an historical case.