RT Journal Article
SR Electronic
T1 Young-onset stroke complicating ulcerative colitis
JF Practical Neurology
JO Pract Neurol
FD BMJ Publishing Group Ltd
SP 220
OP 223
DO 10.1136/practneurol-2021-003106
VO 22
IS 3
A1 Su Yin Lim
A1 Mohamed Sayed
A1 Soma Banerjee
A1 Neil Rane
A1 Dheeraj Kalladka
YR 2022
UL http://pn.bmj.com/content/22/3/220.abstract
AB A 16-year-old girl developed a proximal occlusion of the right middle cerebral artery during a flare-up of acute ulcerative colitis. Although mechanical thrombectomy led to successful middle cerebral artery recanalisation, she required an immediate second thrombectomy due to reocclusion of the same arterial segment. She developed a second ischaemic event 7 days later despite intravenous heparin infusion, later switched to low-molecular-weight heparin, and a third event after 3 days despite the addition of aspirin. We discuss stroke risks in people with inflammatory bowel disease and the uncertainties around anticoagulation and antiplatelet regimens in such cases.