PT  - JOURNAL ARTICLE
AU  - James D Triplett
AU  - Mansur Amirovich Kutlubaev
AU  - Allan G Kermode
AU  - Todd Hardy
TI  - Posterior reversible encephalopathy syndrome (PRES): diagnosis and management
AID  - 10.1136/practneurol-2021-003194
DP  - 2022 Jun 01
TA  - Practical Neurology
PG  - 183--189
VI  - 22
IP  - 3
4099  - http://pn.bmj.com/content/22/3/183.short
4100  - http://pn.bmj.com/content/22/3/183.full
SO  - Pract Neurol2022 Jun 01; 22
AB  - Posterior reversible encephalopathy syndrome (PRES) may present with diverse clinical symptoms including visual disturbance, headache, seizures and impaired consciousness. MRI shows oedema, usually involving the posterior subcortical regions. Triggering factors include hypertension, pre-eclampsia/eclampsia, renal failure, cytotoxic agents and autoimmune conditions. The mechanism underlying PRES is not certain, but endothelial dysfunction is implicated. Treatment is supportive and involves correcting the underlying cause and managing associated complications, such as seizures. Although most patients recover, PRES is not always reversible and may be associated with considerable morbidity and even mortality.