PT - JOURNAL ARTICLE AU - Sahla El Mahdaoui AU - Asher Lou Isenberg AU - Klaus Hansen AU - Annika Reynberg Langkilde AU - Steffen Hamann AU - Jeppe Romme Christensen TI - Acute posterior multifocal placoid pigment epitheliopathy resembling multiple sclerosis AID - 10.1136/pn-2022-003463 DP - 2022 Dec 01 TA - Practical Neurology PG - 515--517 VI - 22 IP - 6 4099 - http://pn.bmj.com/content/22/6/515.short 4100 - http://pn.bmj.com/content/22/6/515.full SO - Pract Neurol2022 Dec 01; 22 AB - A 23-year-old man presented with right eye blurred vision; he was diagnosed with acute posterior multifocal placoid pigment epitheliopathy (APMPPE), and his symptoms resolved with prednisolone. Two months later, he developed a right arm weakness that resolved after 3 weeks. MR scan of brain identified changes suggesting multiple sclerosis, with four hyperintense FLAIR lesions; there was contrast enhancement of two lesions and no diffusion restriction. Cerebrospinal fluid showed mononuclear pleocytosis. We eventually diagnosed these as APMPPE-associated CNS lesions. APMPPE is a rare inflammatory chorioretinopathy that rarely can resemble multiple sclerosis clinically and radiologically.Data sharing not applicable as no datasets generated and/or analysed for this study.