RT Journal Article SR Electronic T1 Acute posterior multifocal placoid pigment epitheliopathy resembling multiple sclerosis JF Practical Neurology JO Pract Neurol FD BMJ Publishing Group Ltd SP 515 OP 517 DO 10.1136/pn-2022-003463 VO 22 IS 6 A1 Sahla El Mahdaoui A1 Asher Lou Isenberg A1 Klaus Hansen A1 Annika Reynberg Langkilde A1 Steffen Hamann A1 Jeppe Romme Christensen YR 2022 UL http://pn.bmj.com/content/22/6/515.abstract AB A 23-year-old man presented with right eye blurred vision; he was diagnosed with acute posterior multifocal placoid pigment epitheliopathy (APMPPE), and his symptoms resolved with prednisolone. Two months later, he developed a right arm weakness that resolved after 3 weeks. MR scan of brain identified changes suggesting multiple sclerosis, with four hyperintense FLAIR lesions; there was contrast enhancement of two lesions and no diffusion restriction. Cerebrospinal fluid showed mononuclear pleocytosis. We eventually diagnosed these as APMPPE-associated CNS lesions. APMPPE is a rare inflammatory chorioretinopathy that rarely can resemble multiple sclerosis clinically and radiologically.Data sharing not applicable as no datasets generated and/or analysed for this study.