PT - JOURNAL ARTICLE AU - Aalaya Haridas AU - Pradeep Ravi TI - Opsoclonus–myoclonus syndrome caused by organophosphate poisoning AID - 10.1136/pn-2022-003612 DP - 2023 Jan 06 TA - Practical Neurology PG - pn-2022-003612 4099 - http://pn.bmj.com/content/early/2023/01/06/pn-2022-003612.short 4100 - http://pn.bmj.com/content/early/2023/01/06/pn-2022-003612.full AB - Opsoclonus–myoclonus syndrome is a combination of involuntary, arrhythmic, conjugate saccadic eye movements with myoclonus. The most common cause in adults is paraneoplastic encephalitis. Rarer causes include infections such as scrub typhus, and toxins such as organophosphates and cocaine. Organophosphates are one of the common poisonings in tropical countries such as India, causing both central and peripheral nervous system manifestations. We describe a middle-aged male farmer with unexplained altered consciousness and respiratory depression. After 2 days, he developed opsoclonus–myoclonus, and then bronchorrhoea and bradycardia, raising suspicion of organophosphate poisoning. After we had identified a very low serum cholinesterase concentration, he disclosed having consumed organophosphates.Data are available on reasonable request.