PT - JOURNAL ARTICLE AU - Yee Yen Goh AU - Emma Saunders AU - Samantha Pavey AU - Emma Rushton AU - Niall Quinn AU - Henry Houlden AU - Viorica Chelban TI - Multiple system atrophy AID - 10.1136/pn-2020-002797 DP - 2023 Mar 16 TA - Practical Neurology PG - practneurol-2020-002797 4099 - http://pn.bmj.com/content/early/2023/03/16/pn-2020-002797.short 4100 - http://pn.bmj.com/content/early/2023/03/16/pn-2020-002797.full AB - This is a practical guide to diagnosing and managing multiple system atrophy (MSA). We explain the newly published Movement Disorders Society Consensus Diagnostic Criteria, which include new ‘Clinically Established MSA’ and ‘Possible Prodromal MSA’ categories, hopefully reducing time to diagnosis. We then highlight the key clinical features of MSA to aid diagnosis. We include a list of MSA mimics with suggested methods of differentiation from MSA. Lastly, we discuss practical symptom management in people living with MSA, including balancing side effects, with the ultimate aim of improving quality of life.Data sharing not applicable as no datasets generated and/or analysed for this study.