RT Journal Article SR Electronic T1 Toxic neuropathies: a practical approach JF Practical Neurology JO Pract Neurol FD BMJ Publishing Group Ltd SP 120 OP 130 DO 10.1136/pn-2022-003444 VO 23 IS 2 A1 Smyth, Duncan A1 Kramarz, Caroline A1 Carr, Aisling S A1 Rossor, Alexander M A1 Lunn, Michael P YR 2023 UL http://pn.bmj.com/content/23/2/120.abstract AB Toxic neuropathies result from exogenous substances damaging the peripheral nerves. There are numerous causes, including prescribed and recreational drugs, heavy metals, industrial agents and biological toxins. Timely recognition of these neuropathies gives better outcomes, as they usually improve or stabilise once the toxin is removed. Most toxic neuropathies are axonal, length-dependent and sensory predominant, although some have significant motor involvement or can present acutely or subacutely. Here, we outline our clinical approach and discuss the major causes of toxic neuropathy, while emphasising the clinical and neurophysiological features and the neuropathy phenotype. We also include an update on newer medications that can cause neuropathy, including immune checkpoint inhibitors and BRAF/MEK inhibitors.Data sharing not applicable as no datasets generated and/or analysed for this study.