RT Journal Article SR Electronic T1 Multiple system atrophy JF Practical Neurology JO Pract Neurol FD BMJ Publishing Group Ltd SP 208 OP 221 DO 10.1136/pn-2020-002797 VO 23 IS 3 A1 Yee Yen Goh A1 Emma Saunders A1 Samantha Pavey A1 Emma Rushton A1 Niall Quinn A1 Henry Houlden A1 Viorica Chelban YR 2023 UL http://pn.bmj.com/content/23/3/208.abstract AB This is a practical guide to diagnosing and managing multiple system atrophy (MSA). We explain the newly published Movement Disorders Society Consensus Diagnostic Criteria, which include new ‘Clinically Established MSA’ and ‘Possible Prodromal MSA’ categories, hopefully reducing time to diagnosis. We then highlight the key clinical features of MSA to aid diagnosis. We include a list of MSA mimics with suggested methods of differentiation from MSA. Lastly, we discuss practical symptom management in people living with MSA, including balancing side effects, with the ultimate aim of improving quality of life.Data sharing not applicable as no datasets generated and/or analysed for this study.