RT Journal Article SR Electronic T1 Strachan’s syndrome and riboflavin deficiency JF Practical Neurology JO Pract Neurol FD BMJ Publishing Group Ltd SP 121 OP 128 DO 10.1136/pn-2023-003822 VO 24 IS 2 A1 Kramarz, Caroline A1 McHugh, James A1 Rossor, Alexander YR 2024 UL http://pn.bmj.com/content/24/2/121.abstract AB Strachan’s syndrome comprises a triad of optic, auditory and painful sensory peripheral neuropathy. It has been recognised since the late 19th century and is presumed to result from nutritional deficiency. Patients present acute or subacutely after a period of systemic illness, weight loss or, most commonly, dietary restriction, especially veganism, which can cause riboflavin (vitamin B2) and vitamin B12 deficiencies. The syndrome is more common in people who are black British and often of Jamaican descent. We describe the clinical phenotype using a typical case example, review other endemic nutritional peripheral neuropathies and discuss the potential benefit of riboflavin as a treatment.Data sharing not applicable as no datasets generated and/or analysed for this study.